Cord Blood & Tissue Treatments

After a baby is born, cord blood is left in the umbilical cord. It is relatively easy to collect, with no risk to the mother or baby. It contains haematopoietic (blood) stem cells: rare cells normally found in the bone marrow.

Haematopoietic stem cells (HSCs) can make every type of cell in the blood-red cells, white cells and platelets. They are responsible for maintaining blood production throughout our lives. They have been used for many years in bone marrow transplants to treat blood diseases.

Umbilical cord blood was once discarded as waste material but is now known to be a useful source of blood stem cells. Cord blood has been used to treat children with certain blood diseases since 1989 and research on using it to treat adults is making progress.

 

Diseases that cord blood stem cells are currently being used to treat:

 

Leukaemias

 

10,100 new diagnosis each year in the UK. That’s 28 every day. There are around 4,700 leukaemia deaths in the UK every year, that’s 13 every day

 

Acute Lymphoblastic Leukemia

Acute Myelogenous Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Lymphoblastic Leukemia

Acute Myelogenous Leukemia (AML)

Chronic Lymphocytic Leukemia (CLL)

Juvenile Chronic Myelogenous Leukemia (JCML)

Juvenile Myelomonocytic Leukemia (JMML)

Refractory Anemia (RA)

Refractory Anemia with Ringed Sideroblasts (RARS)

Refractory Anemia with Excess Blasts (RAEB)

Refractory Anemia with Excess Blasts in Transformation (RAEB-T)

Chronic Myelomonocytic Leukemia (CMML)

Leukaemia success story →

 

Lymphomas

 

13,000 new diagnosis each year in the UK each year. Slightly more men than women are affected.

 

Hodgkin’s Lymphoma

 

Solid Tumours

 

Neuroblastoma

Medulloblastoma

Retinoblastoma

Brain tumour success story →

 

Anemias

 

Aplastic Anemia

Congenital Dyserythropoietic Anemia

Fanconi Anemia

Paroxysmal Nocturnal Hemoglobinuria (PNH)

 

Inherited Red Cell Abnormalities

 

Beta Thalassemia Major (also known as Cooley’s Anemia)

Blackfan-Diamond Anemia

Pure Red Cell Aplasia

Sickle Cell Disease

 

Inherited Platelet Abnormalities

 

Amegakaryocytosis / Congenital Thrombocytopenia

Glanzmann Thrombasthenia

 

Inherited Immune System Disorders

 

SCID with Adenosine Deaminase Deficiency (ADA-SCID)

SCID which is X-linked

SCID with absence of T & B Cells

SCID with absence of T Cells, Normal B Cells

Omenn Syndrome

Kostmann Syndrome

Ataxia–Telangiectasia

Bare Lymphocyte Syndrome

Common Variable Immunodeficiency

DiGeorge Syndrome

Leukocyte Adhesion Deficiency

Lymphoproliferative Disorders (LPD)

Lymphoproliferative Disorder, X-linked (also known as Epstein–Barr Virus Susceptibility)

Wiskott–Aldrich Syndrome

Myeloproliferative Disorders

Acute Myelofibrosis

Agnogenic Myeloid Metaplasia (Myelofibrosis)

Polycythemia Vera

Essential Thrombocythemia

 

Phagocyte Disorders

 

Chediak–Higashi Syndrome

Chronic Granulomatous Disease

Neutrophil Actin Deficiency

Reticular Dysgenesis

 

Bone Marrow Cancers

 

Multiple Myeloma

Plasma Cell Leukemia

Waldenstrom’s Macroglobulinemia

 

Inherited Immune & Other System Disorders

 

Cartilage–Hair Hypoplasia

Gunther’s Disease (Erythropoietic Porphyria)

Hermansky–Pudlak Syndrome

Pearson’s Syndrome

Shwachman–Diamond Syndrome

Systemic Mastocytosis

 

Inherited Metabolic Disorders

 

Mucopolysaccharidoses (MPS)

Hurler’s Syndrome (MPS–IH)

Scheie Syndrome (MPS–IS)

Hunter’s Syndrome (MPS–II)

Sanfilippo Syndrome (MPS–III)

Morquio Syndrome (MPS–IV)

Maroteaux–Lamy Syndrome (MPS–VI)

Sly Syndrome, Beta–Glucuronidase Deficiency (MPS–VII)

Mucolipidosis II (I–cell Disease)

Adrenoleukodystrophy (ALD)/Adrenomyeloneuropathy (AMN)

Krabbe Disease (Globoid Cell Leukodystrophy)

Metachromatic Leukodystrophy

Pelizaeus–Merzbacher Disease

Gaucher Disease

Niemann–Pick Disease

Sandhoff Disease

Tay–Sachs Disease

Wolman Disease

Lesch–Nyhan Syndrome

Osteopetrosis